Berberine Offers Hope for Diabetes, Herpes and Brain Injuries

This is a true story, it is an actual email I received 3 days ago from one of you…

“Dear Suzy,
Five years ago this month I was to ER for emergency surgery….. Hernia cut off my colon…anyway after a year of surgeries and pain I was told I had diabetes 2 devastate me after all I had gone through &survived. I was depressed & scared One day by some miracle I ran across your book! I have read at least 50 times!!!  I have by lived by it for the last two years!
Results: I have lost my 100 lbs …no longer have acid reflux and this week my doctor took me off my metformin diabetic pills & said I no longer need them!!!!!

Thank you for my life!’ ~ Janet W.

Her note brought me to tears! Tears of joy for her, tears of sadness for those of you who remain misdiagnosed, undiagnosed or treated inappropriately.  It made me really think about HOW doctors treat diabetes today, and it brought back a charged memory of “Dottie” a woman in one of my Gainesville Florida nursing homes, who had no arms or legs. Unimaginable and heart-wrenching, the visual is still fresh in my mind 20 years later. 

I consider myself a foodie and would never want to give up traditional desserts and pasta, bagels and muffins. That said, if my blood sugar was elevated I would be highly motivated to alter my diet and try natural remedies before prescription drugs or shots. Twenty nine million people in the United States now have Type 2 diabetes and one in three adults have pre-diabetes, blood sugar levels higher than “normal,” but not quite high enough to be diagnosed with Type 2 diabetes.  Having pre-diabetes puts you on the fast track to getting full-blown Type 2 diabetes within five years. Complications include severe nerve pain, heart disease, kidney failure, blindness, stroke, or amputation of the toes, feet, or legs. Most people don’t know they have diabetes for about 10 years, because they are not tested correctly! You don’t just wake up with diabetes one day, you develop it silently. It’s too bad most people are tested improperly (but I can tell you what to do before it’s too late and the damage is done). Read this article to learn how to test properly.

We know that meal choices matter. We also know that exercising works. The big deal is how low thyroid is the number one missed cause for diabetes. I discuss that in my book, Diabetes Without Drugs. As a pharmacist, I’m aware of the side effects and interactions associated with medications, so today I’m going to spotlight berberine.

Berberine is a compound that scientists extract from the Oregon Grape plant which is the state flower for Oregon in the United States. It grows beautiful yellow flowers and blue grapes (but not the kind of grapes you are thinking of, these are different).

Medicinal uses of berberine have been documented in China since 3000 BC.  More recently, there are scientific papers to show all kinds of cool things! Like how berberine lowers blood glucose (sugar) as effectively as metformin, a popular prescription medicine for diabetes. Doesn’t that just blow your mind?!  Berberine is just as effective as this strong medicine, but without as many side effects. That gets my attention. A study in the Journal of Clinical Endocrinology and Metabolism in 2008 found that berberine caused a significant reduction in hemoglobin A1c (HbA1c) and improved cholesterol ratios. In this particular study, 1,000 mg was administered as the total daily dose.  Another study (animal) suggests that berberine can prevent pre-diabetes from developing.

What else you wonder? Berberine kills herpes simplex virus (HSV) which is often treated with the prescription drug acyclovir. Berberine protects neurons in your brain and reduces inflammation, so it helps with a traumatic brain injury (TBI). Amazingly, when combined with the chemotherapy drug cisplatin, berberine displays strong anti-cancer effects against ovarian cancer cells.

Berberine is completely natural and sold nationwide as a dietary supplement. Most naturopaths recommend 500 mg once, twice or even three times daily. The dosage varies greatly so you should consult a trained professional. Use and dosage depends on your medical history, liver function and the condition for which you are taking it. Keep in mind, berberine is a natural blood thinner. It also enhances the effects of diabetic medications, possibly to your detriment if you blood sugar drops rapidly. It’s definitely not recommended if you are pregnant since it’s a uterine stimulant. Physicians often underestimate herbs but as far as I’m concerned, plants are medicine too.

GlucoScriptClick Here to learn more about this unique, one of a kind all natural supplement for healthy support of  blood sugar and metabolism. I formulated it and yes it does contain berberine.

If you are concerned about diabetes, cholesterol, weight issues, then listen to my FREE presentation at The Diabetes SummitClick Here to get more information on this amazing event.

As may of you already know, I am so proud of the book I wrote Diabetes Without Drugs. This can help many of you as well. I get many wonderful emails from all of you, but this particular one brought me to tears. It is my mission to help alleviate suffering and also my honor to be part of your lives. <3



  1. jill January 24, 2015 at 9:57 pm - Reply

    What hope / cure / or natural relief from painful breakouts can you offer regarding genital herpes?

    • Lisa January 28, 2015 at 12:51 am - Reply

      Hi Emily,

      Most of my research was done on sleep apnea and insulin resistance. There are tons of articles related to sleep apnea (OSA and Central )and diabetes. I have sleep apnea and don’t fit the profile either. Instead of a CPAP machine, I chose a dental appliance.The dentist told me that my tongue was large for my mouth. You may or may not have had a blood test call HgA1C, which measures your blood sugar levels over a 3 month period. This is a good baseline lab reference to have. Diet is important also as well as controlling the sleep apnea.
      Hope this helps,

    • Lisa January 28, 2015 at 12:55 am - Reply

      Hi Jill,

      I would look into ozone therapy. I think that it is one of the most promising therapies out there for many diseases. Make sure your adrenals and hormones are in balance, to avoid any stress on the body


    • Tess January 30, 2015 at 1:04 am - Reply

      Dear Suzy Cohen, I was married for 29 years and my husband gave me genital herpes about 8 years into our marriage. I didn’t know anything about herpes and never had an out break until under marital stress. I would get a small rash on my upper thigh or bottom. I got it tested and I did have herpes. Now I just got divorce a year ago and the rashes stopped until just last week. My questions is although I never got a rash in the vagina and the rash is mild I would rather take something natural like berberine. that I read in your newspaper column. I had mild inflammatory grade 1 on my liver. Can I safely take berberine and how much for the rash outbreak? I am taking acyclovir 400 mg 3X a day.
      Thank you for your time,

      • Suzy Cohen January 31, 2015 at 2:06 am - Reply

        Hi Tess,
        I can’t recommend you (or anyone) “safely take” berberine for a rash outbreak, because I have no idea what is right for you, how you will react, how you will respond to it and what your liver enzymes look like. I wish I could just say take it, or no, don’t take it, but it is not my place.
        Thanks and good luck, and if it’s approved for you by your physician, please come back and tell us if it worked well. I am sure that everyone who takes acyclovir would like to try this too, and would like to know your experience with it.
        PS: I hope you don’t mind, I’ve removed your last name for privacy 😉

    • Pas February 10, 2015 at 9:25 am - Reply

      Spot application of iodine, cut back in high arginine foods, supplement lysine. Take bitter melon, and find stress relief

  2. Barry Yakimchuk January 24, 2015 at 10:03 pm - Reply

    I own “diabetes without drugs” on cd. I have listened to it many times. I am insulin dependant type 2 diabetic. I am lean and muscular. I eat healthy. I consume low carbs and NO sugar at all. I take many vitamins and minerals. I take gymnema,berberind,rla,eleotin,fenugreek,cinamon,aloe vera,vitamin d,and many others. I exercise every day yet I struggle with high blood sugar. I’m lost.

    • Lisa January 25, 2015 at 2:47 pm - Reply

      Hi Barry,
      I understand the frustration you are going through.
      It is hard when you are doing everything right.
      TWO points come to mind that you may or may not be aware of.
      1. Stress-it can play a huge part with your diabetes
      2. Sleep apnea Not widely known, but sleep apnea plays a huge part in diabetes. It is worth having a sleep study.You don’t have to be obese to have sleep apnea.
      I did a lot of research on sleep apnea and diabetes.
      Hope this helps,

      • Emily January 26, 2015 at 8:09 pm - Reply

        Lisa, I am interested in the research you have on the correlation between sleep apnea and diabetes. I was diagnosed with both central and obstructive sleep apnea at 34 but do not fit the typical profile- doctors have never been able to give me a reason. I also have many family members with diabetes. I already have celiac disease and would like to avoid another.

        • Suzy Cohen January 27, 2015 at 4:27 am - Reply

          Hi Emily,
          This has a few citations that might shed light:
          I’ve not studied apnea as my focus so I don’t have any more information. I do know that if you’re overweight, even by 10 pounds the risk goes up for apnea.

        • Lisa January 28, 2015 at 12:49 am - Reply

          Hi Emily,

          Most of my research was done on sleep apnea and insulin resistance. There are tons of articles related to sleep apnea (OSA and Central )and diabetes. I have sleep apnea and don’t fit the profile either. Instead of a CPAP machine, I chose a dental appliance.The dentist told me that my tongue was large for my mouth. You may or may not have had a blood test call HgA1C, which measures your blood sugar levels over a 3 month period. This is a good baseline lab reference to have. Diet is important also as well as controlling the sleep apnea.
          Hope this helps,

      • Barry Yakimchuk May 1, 2015 at 2:49 am - Reply

        Thanx Lisa. I will research this.

    • Theresa January 25, 2015 at 2:59 pm - Reply

      Hi Barry, Have they looked at your pancreatic enzyme output? I wonder if pancreatin would be of help to support your pancreas.

      • Barry Yakimchuk May 1, 2015 at 2:53 am - Reply

        Hi Theresa. I get blood work done every three months. Pancreas is doing fine. I also go for bio- feedback once a month. I will read about pancreatin. Can’t hurt to check it out.

    • C Royle January 26, 2015 at 1:31 pm - Reply

      I just started a book on magnesium deficinet in our diets. I have not conpleted it yet magnesium deficient in our diet can cause many disease including diabetes. t

    • Michele January 28, 2015 at 8:42 pm - Reply

      Hi Barry. I know it’s frustrating, I feel your pain! How low carb are you? How long have you been diabetic & how long have you been doing all these remedies? Sometimes it takes time to heal. Have you seen any improvement? Best of luck, and don’t give up!

      • Barry Yakimchuk May 1, 2015 at 3:00 am - Reply

        Hi Michele. I have had diabetes for about 2 years. I will turn 48 this year. I have been on the herbs, vitamins and minerals for just over one year. My carbs consist of a lot of fruits and vegetables. Sometimes I will eat dark rye bread. I eat approx 100 grams of carbs a day along with a lot of fibre. I am happy to announce that I am now off my insulin. I need to exercise a lot to keep my numbers normal but I am achieving it. I go the gym and lift weights 3 times a week. I also ride my pedal bike approx 300 km per month.

    • Gloria Cole February 9, 2015 at 2:39 pm - Reply

      Barry Yakimchuk. I am a Type 2 diabetic (A1c 5.4). I was able to get off insulin with a vegetarian diet with no sugar, no grains. Lots of leafy greens and rainbow vegetables. But I think intermittent fasting was the most effective habit to incorporate. I stop eating at 4 p.m. and I don’t eat in the morning until 9, 20, sometimes 11. You can adjust the “not eating” time period to suit yourself. I still need to incorporate more exercise. Im thinking of displacing metformin with berberine. I can recommend intermittent fasting (as described at as a strategy for a “stuck” Type 2 diabetic.

  3. Brenda Carroll January 24, 2015 at 10:25 pm - Reply

    Dear Suzy, where can I get a copy of your book Diabetes without Drugs ?

    Brenda C.

    • Suzy Cohen January 24, 2015 at 11:52 pm - Reply

      Hi Brenda,
      Just click on the “shop” tab above, and it will open to my book page. From there, you will see links to them all, just scroll.

  4. Ma uel A. Cardenas January 24, 2015 at 10:56 pm - Reply

    Hi Suzy
    I am exited about you article on type II diabetes, I want to take the class and I like to buy the beberine you indicated, where can I buy it? Whole Food stores?
    Please help me with all information you can provide.
    Also I have under active thyroid and I am taking armour thyroid 120 mg
    What can I do to get healed and be back to normal health? I am taking metaformi g to lower the sugar and my A1C is 8.3
    Thank you very much

    • NanW January 25, 2015 at 4:00 pm - Reply
      I HAVE BEEN TAKING DR WHITAKERs 500 mg but this one is cheaper by half and looks just as good. It works. I am off metfornin, feeling much better. diet very important too. Grain Brain diet by David Perlmutter very good for bringing down AIC.Good luck

  5. Marny Minarsch January 24, 2015 at 11:20 pm - Reply

    I recently read that Berberine is very helpful in treating SIBO. I believe that it
    was Dr. Allison Siebecker who wrote about it.
    Do you have any information about this use?
    Thank you for ALL you do for all of us.

  6. Wendy January 25, 2015 at 1:24 am - Reply

    Does berberine kill Epstein Barr virus (which is a type of Herpes virus)? I need a solution for this virus. I tested greater than 5 for the antibodies. Had mono when I was 19 (I’m 64 now!). Please advise.

    • Suzy Cohen January 25, 2015 at 5:00 am - Reply

      Hi Wendy,
      Berberine might have some activity against EBV, but I think it’s minor. I have heard that Larrea tridentata (Chaparral) may be useful but you have to ask doc if it’s right for you bc I have no idea how you would respond, and if you’d be allergic, etc. So look that up, okay.
      Also, Takuna drops by Nutramedix may have some mild activity.
      LDN to support immune system might be important too. Good luck, keep me posted.

    • Terry Laszlo-Gopadze January 25, 2015 at 6:13 pm - Reply

      Dear Wendy,

      I had active Epstein Barr for years with awful flu/viral type symptoms. My Doctor recommended Metagenics Ultra Clear Renew. Try taking a half scoop everyday for a few months. My symptoms went away and have been gone for about a year!!!! My
      Doctor also has Epstein Barr.

      Good luck!


  7. Mary Schleicher January 25, 2015 at 3:56 am - Reply

    For someone like Barry who seems to be doing everything right, but their sugar stays elevated. I just seen a piece about “starch resistant carbs”. Like having Green bananas, and white rice that’s eaten cold, not bad with canned coconut milk and organic cinnamon, which helps lower sugar. Raw potatoes, lentils. Google it, I’m sure there’s more. Some just seem to be more genetically disposed to high blood sugar. You’re probably consuming coconut oil, which is excellent, lemon juice to alkalize your system. No ripe bananas, or many berries, only 2 servings of fruit a day. Apples, oranges, , No juicing which concentrates the sugar in food. Hope some of this helps. Suzy Cohen has some great information, really appreciate her sharing what she knows, so we can be empowered to make the right decision when it comes to our health.

  8. Dalien Pedro January 25, 2015 at 6:42 am - Reply

    When you eat and exercise correctly and blood sugar is still not under control? Take care not to consume alcohol in any form.

  9. Dee January 25, 2015 at 2:34 pm - Reply

    Suzy, does sucralose (sweetener) affect blood sugar?

    • Suzy Cohen January 25, 2015 at 6:38 pm - Reply

      I never recommend artificial sweeteners.

    • Sharon April 3, 2015 at 6:44 pm - Reply

      Dee, I have switched to Stevia, alcohol- free by Swanson vitamins best tasting and won’t rise blood sugars.

  10. Elaine Fleming January 25, 2015 at 5:27 pm - Reply

    My mother is 91. All her labs are normal except blood sugar and hemoglobin A1c. She has been a whole food, high unrefined carb vegan for 40 years. She stopped fruit and toast, against my protests, with no improvement in her blood sugars. Two days of metformin made her sick and depressed. I checked–it blocks methylation! So I looked online for natural remedies that have the same metabolic action as metformin. I found a clinical trial that showed the barbering could stand up to metformin, as Suzy said! It also decreases total cholesterol, something my mother does not need since she’s around 150. Well, I read that berberine didn’t lower cholesterol for those not needing it lowered! My mother’s blood sugars are normal now for months, and never a side effect, even for this frail, tiny little lady. She seldom ate deserts, maybe a couple spoons of something, but she is eating her usual diet again including her beloved fruit and whole wheat toast. I am a retired nutrition professor. Thank you, Suzy, for your courage and care for us.

    • Carolyn March 25, 2015 at 3:28 pm - Reply

      Elaine, thank you for the information about your 91 year old mother! I am 81, and it is encouraging to hear of her success.

  11. Tammy January 25, 2015 at 7:28 pm - Reply

    How much berberine would one take to deter herpes outbreak?

  12. Bella January 25, 2015 at 7:30 pm - Reply

    Thanks for this great info and all you do Suzy!
    Do you recommend taking Berberine regularly for herpes or during breakouts?

  13. Tony January 26, 2015 at 6:50 pm - Reply

    Wild Oregano Oil is also good to control herpes outbreaks as well as fight off cold and flu bugs.

    • Suzy Cohen January 27, 2015 at 4:32 am - Reply

      Yes, excellent point Tony. Only thing is if you have an undiagnosed infection or a fungal infection you are going to get a huge herx, just saying. But yes, the oregano oil is some awesome stuff.

    • Jo February 15, 2015 at 4:20 am - Reply

      L- Lysine, 500 mg, in capsule form is very effective in healing the blisters of herpes simplex, and for small “burn” blisters. It quickly reduces all associated pain, itching, and swelling. I usually take 1,000 mg. 2 or 3 times daily for just a few days.

  14. Jason January 26, 2015 at 7:12 pm - Reply


    Great article. Thank you so much for your wisdom. Do you have a particular brand of Berberine you recommend? Thanks,

    • Suzy Cohen January 27, 2015 at 4:28 am - Reply

      Whatever you feel drawn to. I use Thorne Research’s brand when I take it but I also have an account with them. Not 100% sure if they sell to lay people… ah I see now you are a doctor 🙂
      Yep, you can try Thorne, or see if it’s on Amazon.

  15. K January 27, 2015 at 4:33 am - Reply

    Suzy mentions that Berberine lowers hemoglobin levels. For someone with anemia and low levels of hemoglobin should I avoid this herb?

    • Nancy Rothrock February 1, 2015 at 4:32 am - Reply

      She does not say it lowers hemoglobin, she said it lowers the sugar levels in a hemoglobin A1c test.

  16. Margaret January 27, 2015 at 12:54 pm - Reply

    Thorne Research’s Berberine is available from There’s a 500 mg one (out of

    stock just now when I looked it up) and a 200 mg one. If it’s a first time order, you can get

    either $5 or $10 off by putting RAL603 in the appropriate spot, depending how much you

    order. They carry many excellent brands at good prices.

    • Margaret January 27, 2015 at 12:59 pm - Reply

      I’ve used Berberine in the past and this is where I found it.

  17. Jandroid February 1, 2015 at 6:37 am - Reply

    I would strongly urge all who experience both kinds of sleep apnea (Central Nervous System and obstructive airway) to look into connective tissue disorders *regardless of your weight*. We find this issue very common in the Ehlers-Danlos Syndrome community at all body sizes. EDS is a genetic collagen defect that causes a mind-blowing array of issues from weakened tissues all over the body that may run in as much as 2% of the population. (Many with fibro later find they have a form of it). I had a “bout” of CNS apnea during my EDS onset “storm” of 2012, when I essentially fell apart rather suddenly and completely head to toe at 45. I was so busy just trying to manage and stay fed/watered I never got it treated properly. But I had trouble breathing *even in the daytime* during the worst part, and I now think it was from cranial-cervical settling in 20/20 hindsight. (Several colleagues with EDS have experienced the same.) Good news: I’ve restrengthened a bunch since starting high dose vitamin C plus calc, mag, zinc, D3 and my CNS apnea is gone. You might try wearing a soft cervical collar at night too, and see if helps. Learn more:

  18. Kitty February 2, 2015 at 4:34 am - Reply

    Berberine kills herpes simplex virus (HSV) which is often treated with the prescription drug acyclovir.

    Does this kill the virus so it never comes back or just manages outbreaks?

  19. Hasan February 3, 2015 at 8:20 pm - Reply

    Hi there

    Where does one start my life has been turned upside down by herpes 2 I was diagnosed in 2009 haven’t had another until 2012 it was like full body attack I have had obs every week since then I have had 4 of in January 2015 alone , I am taking antiviral a and that is not helping , I am healthy I sleep early I don’t drink or smoke never have. Is there anything you can advise me to lessen the outbreaks ?

    Thank u

  20. Steve February 3, 2015 at 8:27 pm - Reply

    From the BloodSugar101 website. Your readers should be aware of this info.

    Several mainstream studies claims to have found that berberine inhibits DPP-4 and raises the concentration of the incretin hormone GLP-1 which is the mechanism used by the incretin drugs Januvia, Onglyza, and Trajenta. As discussed elsewhere, inhibiting DPP-4 can turn off a mechanism the immune system uses to kill cells that have become cancerous, which may make these a poor choice of drug. In addition, accumulating evidence is pointing to the possibility that artificially raising GLP-1 levels over a long period of time leads to the growth of abnormal cells in the pancreas which may grow into the ducts and cause pancreatitis or turn into precancerous tumors.

    Mainstream research also finds that berberine has a significant impact on your liver. Repeated use downregulates several important enzymes (P450 cytochromes ) that the body uses to eliminate drugs.

    This means that if you are taking berberine, other drugs you take may not be eliminated properly if they use those enzymes and may build up to toxic levels, while others, which require those enzymes to be working so that the drug can be broken down into the active form of the chemical they contain may not work as expected.

    In particular you should not combine repaglinide (Prandin) with berberine as that combination may produce hypos since repaglinide is eliminated from the body by an enzyme that berberine inhibits. Since metformin also inhibits one of these enzymes to some extent, combining berberine and metformin is probably a bad idea, too.

    Other drugs affected by berberine include cyclosporin (Neoral, Sandimmune), lovastatin (Mevacor), clarithromycin (Biaxin), indinavir (Crixivan), sildenafil (Viagra), triazolam (Halcion), and many others.

    As always, when you buy an unregulated supplement, you have no way of knowing what is actually in the pill. Herbs grown in third world countries often contain toxic herbicides which are prohibited in the U.S.. And supplements manufactured abroad may also contain lead and other toxic heavy metals, as well as other contaminants. As supplements are completely unregulated in the U.S. and receive no scrutiny unless they kill someone, the assurances of the supplement companies that their supplements are “pure” are worthless. When supplements are taken to the lab by consumer groups, they often turn out to contain different dosages thatn what the label claims and to be contaminated.

    With all this in mind, it seems prudent if you are going to use a drug to lower your blood sugar, to stick to drugs that are regulated, provided in pills of known dosage, and which have long track records for safety. Currently, the only drugs that fit that description are: metformin, insulin, prandin, gliclazide (not available in the U.S.) and acarbose.

    • Sam April 3, 2015 at 9:53 pm - Reply

      Thanks for dashing any tiny glimmer of hope I had.

  21. Gloria Cole February 9, 2015 at 2:57 pm - Reply

    This article discusses the effect of berberine on gut bacteria.

    Elsewhere, I read that as a control for diabetes you should only take berberine for 7 days and then stop to allow gut bacteria to revive. I don’t think most people would want to ingest a substance that destroyed gut bacteria. But, that doesn’t seem to be what the Chinese study is saying. It does however say that berberine radically alters gut bacteria–is that an adaptive response or a maladaptive response ?

    • Suzy Cohen October 26, 2015 at 11:54 pm - Reply

      Hello Gloria
      I got rid of the spammish-comment, we get hundreds and hundreds of comments per day, so hard to keep up. Thank you 🙂
      I think berberine in low doses is okay for a while (beyond 7 days), I haven’t heard it harms the microbiome. High doses of berberine, like 500 to 1000 per day for long periods of time are not good. I’m not sure if it’s adaptive or not. I’ll remember this and keep it in the back of my mind.

  22. Hope February 9, 2015 at 7:46 pm - Reply

    suzy I’m interested this article because I have a 28 yr old son with seizures since he pulled a shopping cart (accidently) down on his head and nose at Walmart when he was 6 years old. Can berberine help with seizures ? I found you on Doug Kaufmann program several years ago and I have bought your books and given and recommended your books to many people. In constantly on the look out for something safer to help with seizures. He currently takes lamictal with limited success at best…

  23. anatoly arutunoff February 13, 2015 at 11:38 pm - Reply

    In the early ’70s there was a full-page article in the L.A. Times about an Air Force hospital putting diabetics on a complete fast for–possibly weeks? Anyway a large percentage of the young people so treated (all service members as I recall) recovered completely.

  24. Elle March 9, 2015 at 3:27 am - Reply

    Does the information in your book, Headache Free, apply to Traumatic Brain Injuries?

    • Suzy Cohen March 9, 2015 at 4:07 am - Reply

      Yes it could I have a section on TBI in the “mystery headache” chapter. The same pain and inflammation compounds are high in TBI as they are in migraines so there’s a ton you could learn.

      • carol kloes March 24, 2015 at 10:18 pm - Reply

        My son has a tramatic brain injury. Had a hang gliding accident. He does not have headaches but no short term memory. Would the Berberine help for that? His accident was 17 years ago. He is now on a prescription for Alzimers. THANKS for all your articles. EXCELLENT.

        • Suzy Cohen March 26, 2015 at 6:36 am - Reply

          Hi Carol
          I’m sorry to hear about your son, that must have been very hard on you! The prescription drugs for Alzheimer’s offer a suitable workaround but they are not curative (as you know). I’m uncertain about berberine for this, you can certainly ask doc if it’s okay to try since doc has his personal/private medical history, allergies and/or genes. Have they tried anything else? Essential fatty acids, eulethero, or vinpocetine??? I am not sure if those could help so please read about them, use my search box. They’re not right for everyone. Keep me posted.

  25. jan owens March 19, 2015 at 1:58 pm - Reply

    I have been on diabetic medication for at least 5 years. I was still “uncontrolled” and was never to bring my daily levels under 155. My A1C has fluctuated between 7.0 and 8.9 and it was difficult to have any stability at all! I decided to go off the medication and start the berberine. I titrated the meds and at the same time started the berberine. After one week I started seeing results! I slowly decreased by daily levels and am now tetering between 80 and 109. What a difference this makes to my health, my wellness and how I feel. I will not go back on that medication again! Thanks for all the advice and information you give that helps those of us on meds, to rethink what we are doing and take another look at possible alternatives!

  26. Crystal April 6, 2015 at 1:10 pm - Reply


    Is berberine safe to take with naturethroid?

  27. Em April 16, 2015 at 3:24 am - Reply

    Hi Suzy,
    I have hashimoto’s and take synthroid and cytomel ( t4 and t3). Also have adrenal fatigue and some resulting blood sugar issues on the higher end and insulin resistance. I have heard adrenals also impact liver health. Can berberine negatively impact the livers functioning and or thyroid function?
    Great article!

  28. Jim June 15, 2015 at 7:13 pm - Reply

    Hi Suzy,

    Berberine has been marketed as a medicinal substance in the USA since the 1800s, but it has only fairly recently hit the shelves as a dietary supplement. Would you happen to know how long berberine-containing supplement have been marketed in the United States?



  29. Jenny June 26, 2015 at 12:05 pm - Reply

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  30. Anne August 25, 2015 at 9:50 pm - Reply

    How does berberine affect insulin levels? My dr has me on megadoses of metformin not becuase my blood sugar is that high (my a1c is around 5.6) but my insulin fasting level is extremely high (ususally over 40) and higher than most diabetics. So far though i can barely take 1 500 mg dose of metformin and I’m supposed to take 5 doses a day! anything else you know natural that will lower insulin?

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