Why Cells Don’t Absorb Thyroid Hormone

No matter what medication you take, or how much T4 your thyroid gland produces, it doesn’t matter if the cells aren’t taking up the thyroid hormone. In other words, you can take (or make) thyroid hormone, but if you have cellular resistance, or some issue that prevents your cells from taking it up, you are still going to be hypothyroid and experience symptoms of the condition.

Symptoms vary but may include hair loss, fatigue, heart palpitations, anxiety, feeling cold, frequent infections, infertility, weakness, shortness of breath, problems with PMS and much more. 

Many factors influence this cellular uptake. See the graphic I made for you here. I’m trying to show you how thyroid hormone has to penetrate the cell membrane, as well as the nucleus in order to do its job. Many things can interfere with that process, leaving you hypothyroid despite the medication you’re taking.

1. If you have Hashimoto’s, your TPO antibodies will be higher than normal, and this prevents cellular uptake to some degree. If you’d like more information on rT3, click to read Measure Reverse T3 and Get Healthy.

2. High levels of rT3 will reduce uptake

3.  Abnormal cortisol, either high or low levels. You could be high in cortisol during stressful periods of your life, or you may be totally depleted if you’ve endured many years of chronic illness or stress. Levels can be tested via urine. 4. Insufficient bioavailable vitamin D, ideally you want the number to be 40 – 50.  FYI, don’t over-supplement with D, it can cause mild heart palpitations. Take a nice amount, that’s right for you, don’t take excessive amounts. I see people taking 10,000, 20,000 and 50,000 IU.  That is likely too much 😉

4. Mineral deficiencies such as low zinc and low iron. This can happen to people who use antacids, or take heartburn/reflux pills. Also, it can happen to women who use oral contraceptives which are drug muggers of some of these important minerals.  A heavy period for a long time will cause iron deficiency. Low levels of these minerals means that you can’t pull in the thyroid hormone like you should, and might wind up deficient.

If you’d like to read more on this subject get my free ebook, Hypothyroidism: 5 Reasons You Don’t Get Well.

Or you can order a copy of this beautiful 150 page magazine with dozens of tips, recipes and thyroid, adrenal and hormone information: The title of the magazine is Health & Radiant Aging.


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